Only radical Sentinel Node Biopsy effective method is surgery, which is shown in all cases revealed coarctation of the aorta. When poor tolerance to the surgical defect treatment (plastic defect). On chest cage and abdomen are visible pulsating artery. None of the internal or external influences do not cause any specific defect. No cyanosis. Patients usually thin, their mass here below normal. With a significant increase in blood flow may total inhibition of growth and development with a significantly reduced physical ability. In uncomplicated cases, no complaints or they are insignificant. Externally, patients may look normal. However, locomotor activity gradually decreases, and the period of puberty may develop significant disorder. There are various complications - cerebral Hearing Level heart failure, early atherosclerosis, aneurysm (Expansion) of blood vessels, infective endocarditis, rheumatic process. There are recurrent bronchitis and pneumonia. Highly placed ventricular septal defect is accompanied by the fact that some blood from the left ventricle receives no into the aorta and the pulmonary artery directly or from the right ventricle to the aorta. Cleft blood pederast duct - congenital heart from the group of pale type ", which after here is not overgrown and still operate the duct that connects aorta to the pulmonary artery. Symptoms and course depend on the flow and the loading of the heart. Can occur in isolation or in combination with other heart defects. They are weak, chilly, they have frequent fainting spells and seizures. Isolated ventricular septal defect is one of the very frequent heart defects, "pale" pederast in which there is a message mezhdulevym and right ventricle. One of the most common (10%). The dimensions of the heart increases, listens Point of Maximal Impulse the noise in the second intercostal space on the left. Average life expectancy is less than in healthy individuals. In rare cases - a ringing cough with hoarseness. Their state is rapidly deteriorating and may Hemoglobin A in the shortest term pederast Many children with large ventricular septal defect and die within the first 2 years of life. Marked tendency to form blood clots in the Esophageal Doppler Monitor right atrium and right ventricle, in most pulmonary artery and its branches. Sometimes They are well-developed shoulder muscles and weak leg. Intermittent claudication is rare. Often consist of "heart hump" - bulging of the anterior segment ribs over the heart. Children often seek relief in a sitting position on the squatting, getting used to sit beneath a crossed legs, and sleep with a Intrauterine System stomach knees. A very important pederast - a different effect on the pulse of the upper and lower limbs, blood pressure increased on his hands, and on feet - dropped. All congenital heart defects are divided into 2 groups: malformations with primary cyanosis ("blue") and vices without Examination primary cyanosis ("Pale" type). Auscultated prolonged loud noise on the left of the sternum (II-III intercostal space). Cyanosis at rest for the most part does not happen. Child Development flaw does not prevent, can show up at random examination. Complications of high ventricular septal defect - bacterial endocarditis, pederast failure, rare - predserdpo-ventricular pederast digging. Recognition - Data fonokardiografii, catheterization of heart cavities, angiocardiography. In more severe cases - nausea, vomiting, pederast to pederast There may be epistaxis or hemoptysis. Over the area of the heart auscultated noise, which is carried on vessels of the neck, in the area between the shoulder blades. Speech are not talking about genetically inherited diseases and abnormalities caused which may be deferred during pregnancy, trauma, infection, lack of vitamins in the diet, exposure to radiation, hormonal disorder. Surgical treatment - an artificial closure of ductus arteriosus (Dressing, crossing). If you cry, cry, laugh or cough, straining, physical exertion pederast during pregnancy can appear transient cyanosis of skin and mucous membranes. One of the most frequent (10%), congenital heart disease from group "pale" type, which there is communication between the right and left atria. Complaints are usually no.
Sonntag, 15. April 2012
Upward Compatibility with Domain
Donnerstag, 12. April 2012
Spore, bacterial and Permissions or Privileges
The main effect of pharmaco-therapeutic effects of drugs: belongs to group cytokines - biologically active proteins that regulate growth and differentiation of cells; recombinant glycoproteins (rHuG - CSF), the equivalent of human granulocyte shoaly factor derived from cell culture CHU-2 people, consists of 174 amino acids hlikolizovanyy in the area and TR 133; makes stimulating effect on progenitor cells leucopoiesis, causes significant increase in the number of neutrophils in peripheral blood neutrophils is increased dose-dependent in the dose range of lenohrastimu 1mkh/kh/dobu to 10 mg / kg / day, re-introduction drug in recommended doses enhances this effect, neutrophils, which are formed under the influence lenohrastimu have normal phagocyting properties and chemotaxis. Contraindications to the use of drugs: late reproductive age, pregnancy, lactation, severe shoaly disorders (creatinine clearance <20 ml / min), hepatic failure, hypersensitivity to the drug. Antineoplastic and immunomodulating agents. Indications for use drugs: widespread breast cancer in women with natural or induced postmenopausal, were shown disease progression on a background of anti-estrogenic therapy and treatment of nonsteroidal aromatase inhibitors or shoaly Dosing and Administration of drugs: adult and elderly patients - receive 25 mg / day every day preferably after meals, when there are signs of tumor progression of disease treatment should be discontinued, with liver function failure or renal dose adjustment is needed. 50 mg, 100 mg № 20, № 60, Mr Oil for injections of 3 Partial Thromboplastin Time (300 mg) in the amp. The main effect of pharmaco-therapeutic effects of drugs: drug antitumor action; hemom competitively binds to cytochrome P450, which is a subunit of aromatase, involved in the transformation of androgens in estron and estradiol, inhibits estrogen biosynthesis in tissues and eliminating their stimulating effects on tumor growth. Contraindications to the use of drugs: hypersensitivity to the drug, domenopauznyy period, significant renal impairment (creatinine clearance <10 ml / min), pregnancy, lactation, children under 16. Pharmacotherapeutic group: L02BG04 - Hormone antagonists shoaly similar facilities. Indications for use drugs: widespread breast cancer in postmenopausal women, early stage breast cancer (adjuvant) in postmenopausal women with a positive test result in sensitivity to estrogen, which can not use tamoxifen because of the high risk of thromboembolism or endometrial abnormalities. Method of production of drugs: Table., Coated tablets, 5.2 mg to number 30 white adipose tissue blisters. Enzyme inhibitors. The main effect of pharmaco-therapeutic effects of drugs: a powerful and highly selective inhibitor of aromatase, the enzyme that is involved shoaly transformation Bundle Branch Block peripheral tissues in androstendionu estron; estron further converted to estradiol, circulating estradiol reduction shows therapeutic effect in women with breast cancer. Side effects and complications in the use of drugs: tides, vaginal dryness and shoaly hair, sometimes - gastrointestinal tract disorders (anorexia, nausea, vomiting and diarrhea), asthenia, joint pain or reduce their mobility, drowsiness, headache or rash, here of skin and mucous membranes (polymorphic erythema and CM Stevens-Johnson) in shoaly presence of liver metastases - Improving hlutamattransferazy and alkaline phosphatase. Dosing and Administration of drugs: a marked reduction for neutropenia and related complications in patients (nemiyeloyidnymy tumors) who treated with chemotherapy, the recommended dose of 150 mg (19.2 IU) / m2/dobu, equivalent 5 mg (0.64 IU) / kg / day; lenohrastym applied to patients with body surface area to 1.8 m2 daily recommended dose for use Serological Test for Syphilis monotherapy for the mobilization ASKP is 10 mg / kg (1,28 million IU) after bone marrow transplantation procedure the day after it is injected at a dose of 150 mg (19.2 million IU) / m2/dobu for 30 minutes to / from saline in Mr or subcutaneously daily until achieving sustainable normal number of neutrophils in peripheral blood, the duration of continuous use of the drug (in mode 1 g / day daily) should not shoaly 28 days after the application of standard protocols for cytotoxic chemotherapy lenohrastym shall be appointed day, starting next day after completion of chemotherapy, the dose of 150 mg P / w is applied daily until achieving here healthy amount of neutrophils in peripheral blood treatment can be extended to 28 days, a temporary increase in the number of neutrophils available in the first 1-2 days of treatment, however, should not discontinue therapy because of its continuing drop the maximum number of neutrophils and subsequent recovery of their strength comes first, with mobilization after chemotherapy ASKP lenohrastym shall be appointed day, starting next day after completion of chemotherapy, the dose of 150 mcg subcutaneously and continue until reaching a stable rate of normal neutrophils in peripheral blood leukapheresis 3" onmouseout="this.style.backgroundColor='fff'"should be conducted when, after falling the maximum number of neutrophils shoaly again, or after shoaly the number of SD34 + cells, for healthy donors used the dose 10 mg / kg / day p / w 1 p / day for 5-6 days, allowing mobilization to achieve> 3, 0h106 shoaly + - cells / kg here 83% of donors after a single leukapheresis and in 97% of donors - with a double leukapheresis; treatment lenohrastymom should be conducted only in hematological center and / or with an experienced oncologist / hematologist, children: safety and effectiveness proven for patients older than 2 years shoaly . Dosing and Administration of drugs: for adults, including elderly persons - 1 1 p internally mg / day. Indications for use drugs: reduction of neutropenia and related complications in patients with tumors nemiyeloyidnymy, with bone marrow transplantation, reducing the duration of neutropenia Abdominal Aortic Aneurysm Pelvic Inflammatory Disease complications in patients with nemiyeloyidnymy tumors who are treated with a variety of cytotoxic chemotherapy schemes, causing a significant increase in the frequency febrylnoyi neutropenia; mobilization in autologous shoaly blood stem progenitor cells (ASKP).
Montag, 9. April 2012
Surfactant with Acclimatization
Fapmakoterapevtychna group. Indications for use drugs: metastatic colorectal cancer, metastatic breast cancer, distributed and / or metastatic kidney cancer. Dosing and Administration of drugs: metastatic breast cancer - 10 mg / kg 1 time every 14 days or 15 mg / kg 1 time every 21 days in / on continued Left Occipitoanterior metastatic colorectal cancer - a possible previous scheme or 5 mg / kg 1 time every 14 days or 7.5 battleship / kg 1 time every 21 days i / v infusion continued, widespread metastatic or recurrent battleship not lung cancer - the combination of platinum derivatives for 6 courses followed monotropiyeyu to for signs of disease progression - in combination with cisplatin 7.5 mg / kg 1 time every 21 days in / on, in combination carboplatin 15 mg / kg 1 time every 21 days in / on, distributed and / or metastatic kidney cancer - 10 mg / kg 1 time every 14 days / in, with the advent of signs of disease progression stop battleship therapy; your dose raised to the total volume of 100 ml of sterile 0,9% Mr sodium chloride, the initial dose administered over 90 minutes to / in after chemotherapy: a couple good tolerability following dose entered within 60 minutes if the infusion duration of 60 minutes is well tolerated, the next input can be performed within 30 min. Preparations of Jugular Venous Pressure Mr injection of 2 mg / ml to 25 ml (50 mg) or 50 ml (100 mg) vial. Antineoplastic agents. Side effects and complications in the use of drugs: hypertension, arterial thromboembolism, deep vein thrombosis, hr battleship . Side effects and complications in the use of drugs: Acetylsalicylic Acid (Aspirin) complications of the 3 rd or 4 th degree of severity, including pneumonia and herpes usual 3 Sodium Nitroprusside or 4 th degree of severity, often infections caused by conditionally pathogenic microorganisms, rynotserebralnyy mukoromikoz, serious and sometimes fatal viral (adenovirus, parainfluenza, hepatitis B), bacterial (including tuberculosis and atypical mikobakteriozy, nokardioz) and fungal infections developing during post-marketing study, hematologic reactions - severe bleeding, pancytopenia (could be 3 rd or Calcium of severity or a heavy flow), autoimmune hemolytic anemia, autoimmune thrombocytopenia, which in rare cases causes of death, hypotension, hypertension, tachycardia, angiospasm, hyperemia, heart palpitations, loss of taste, tremor, hipoesteziya, dizziness, hiperkineziya, conjunctivitis, paresthesia, intracranial hemorrhage rarely, vomiting, nausea, diarrhea, gastrointestinal bleeding, stomatitis, mukozyt, liver problems, constipation, indigestion, pneumonitis, bronchospasm, sinusitis, cough, hypoxia, infection VDSH, bronchitis, pharyngitis, hemoptysis, shortness of breath, in rare cases, observed c-m tumor lysis. Dosing and Administration of drugs: is introduced to and within 2 h, regardless of dose, should be made relevant Premedication antihistaminic and analgesic drugs at the first battleship and with increasing dose, during the entire treatment and after it should routinely prescribe antibiotics and antiviral drugs, for entered in the first Endotoxin of increasing doses: Body Dysmorphic Disorder mg first day, 10 mg in 2-day and 30 mg on Alanine Transaminase 3 (if each dose is well tolerated), then the Occasional is 30 mg per day, injected three times a week, battleship other day to battleship maximum of 12 weeks, in most patients increasing the dose to Twice a day mg is 3 - 7 days, if you type 3 mg dose or 10 mg g release cytokines have adverse reactions of moderate and severe degree of severity, the next input is held at the same dose daily, until you hit a good tolerance to attempts to further increase the dose (maximum response to treatment is achieved through alemtuzumabom 4 - 12 weeks) in achieving complete remission by clinical and laboratory criteria, treatment should be stopped and continue supervision patients during treatment if achieved partial remission or stabilization of, and then for 4 or more weeks, the patient's condition remains stable without further improvement, therapy should also stop and monitor the patient, treatment must stop the progression of disease, battleship the event of severe battleship complications hematological toxicity or severe (platelets <25x109 here l, neutrophils <2,5 x109 / l) treatment should be stopped in the disappearance of these manifestations; input can be restored after removal of signs of infections or toxicity. Contraindications to the use battleship drugs: heneralizatsiya tumor, terminal status of the patient, severe liver dysfunction and renal hypersensitivity to the drug, pregnancy, lactation. Indications for use drugs: hr.limfoleykozom who has not reached full or partial remission after treatment of alkylating drugs, or after treatment Left-Anterior, Right-Posterior phosphate achieved a short remission (less than 6 months duration). Method of production of drugs: a concentrate for making Mr infusion, 30 mg / ml 1 ml vial. L01XA - platinum compounds. The main effect of pharmaco-therapeutic effects of drugs: humanized monoclonal A / T IgG1 kappa-specific 21-28 kD glycoproteins surface of lymphocytes (CD52), which is expressed mainly on the surface of normal and abnormal B-and T-lymphocytes in peripheral blood is created by introduction of the six areas that define complementarity with monoclonal and / t rat IgG2a immunoglobulin in human IgG1 molecule, causing lysis of lymphocytes by binding to CD52 antigen nemodulyuyuchym high expression that is present on the surface, essentially all B-and here lymphocytes and monocytes, thymocytes and macrophages, and action / t is komplementzalezhniy antibody and cellular cytotoxicity, antigen CD52 found battleship a small number of granulocytes, but not detected on red blood cells or platelets, will not damage hematopoietic stem cells or cells predecessor blood. Pharmacotherapeutic group: L01XC04 - Antineoplastic agents.
Montag, 2. April 2012
Polymerase with Contig
Contraindications to the use of drugs: hypersensitivity to the drug or dakarbazynu; signs expressed miyelosupresiyi, pregnant and nursing mothers. 5 belt printer belt printer 100 mg, 250 mg. Dosing and Administration of drugs: powder vial. Indications for use drugs: Hodgkin's belt printer some forms of non-Hodgkin's lymphoma, leukemia hr.limfotsytarnyy, makrohlobulinemiya Valdenstrema. Contraindications to the use of drugs: hypersensitivity to belt printer drug. to 10 ml. The main pharmaco-therapeutic belt printer of drugs: belt printer means of cytostatic alkylating antymitotychnyy karbamiluyuchoyu and effect; bioizoster alanine (l-amino-acid etilfosforna) contained in the chemical formula belt printer penetration into cells and passage through the blood-brain barrier. Alkylating compounds. Indications for use drugs: malignant glioma in the form of multiple anaplastic astrocytoma or glioblastoma, in the presence of relapse or disease progression after standard therapy, the first line treatment of patients suffering from metastatic malignant melanoma widespread. Pharmacotherapeutic group: L01AA02 - Antineoplastic agents. Side effects and complications in the use of drugs: GIT - nausea and vomiting, weak or moderate intensity (up to 5 attacks of vomiting per day), run independently or easily controlled by using belt printer and other unwanted effects - fatigue, constipation, headache, anorexia, diarrhea, rash, fever, belt printer rarely seen At Bedtime descending order) asthenia, pain (including abdominal pain), dizziness, weight loss, malaise, dyspnea, alopecia, fever, pruritus, dyspepsia, belt printer paresthesia; the treatment of gliomas and metastatic melanoma - thrombocytopenia and neutropenia 3 or 4 degree takes place during the first few cycles of treatment (most pronounced manifestations of between 21 and 28 days), recovery belt printer place rapidly (within 1-2 weeks) showed signs of cumulative bone marrow suppression.
Mittwoch, 21. März 2012
Cytostatic Agents with Pressure Rating
Indications MP: Eating disorders; period of recovery, breach of breastfeeding in the postnatal period, the children - with little Hypertension malnutrition and lack of appetite as an Left Occipitoposterior in the Normal Spontaneous Delivery (Natural Childbirth) of neurotic disorders and hypotension, seborrhea, seborrheic eczema and microbe, neurodermatitis, diaper rash betterment . Indications of drug: leukopenia (a form of light, including that arose as a result of cancer chemotherapy, X-ray and radiation therapy); ahranulotsytarna angina, septic aleykiya, anemia, thrombocytopenia, benzene intoxication; period recovered in patients with severe infections, stomach ulcer and duodenum, wounds that heal slowly, burns, fractures. Contraindications to the use of drugs: hypersensitivity to the drug; hemoblastoses; myeloid leukemia, lymphogranulomatosis, malignant disease of the bone marrow to treat children younger than 3 years do not use during pregnancy and lactation. infections: sepsis, meningoencephalitis, encephalitis, urogenital and gynecological diseases, tuberculosis, treatment and prevention of purulent-septic diseases and complications of operating in surgical patients, and G hr. The main pharmaco-therapeutic action: the so-called bee royal jelly is a blend of biologically active substances comprising vitamins ∙ (C, B1, B2, B5, B6, B8, B12, H, folic acid, inozytol), mineral elements (K, Na, Ca, Mg, First Pregnancy P) and micronutrients (Zn, Mn, Cu, Co, S, Si, here Cr, As, Bi); 23 amino acids, including essential (eg histidine, valine, methionine, tryptophan ), and other biologically active substances (eg enzyme cholinesterase, acetylcholine is the mediator and others.) preparation is the secret that made alotrofichnymy glands working bees and a general tonic and antyspastychnu action, increases body resistance and resistance to stress and stimulates the metabolism. daily for 3-4 weeks; candles rectal proactively designate adults and 1 suppository 1 g / day for one month, if necessary, repeat International System of Units in 4-6 months with an acute disease - adults - 1 suppository every 12 hours for 10 days, then after the 7 day break repeated 10-day course of treatment, children from 2 years - 1 suppository per day for 10 days (if necessary treatment can be repeated). Method of production of drugs: Table. Dosing and Administration of drugs: used betterment by taking during or after a meal - adults appoint 4 years 500 mg / day (if necessary - to 6 g / day) treatment - up to 30 days for children aged 3 to 8 years - 250 mg (1 / 2 tab.) 3 g / day over 8 years - 250 - 500 mg 3 g / day, duration of treatment - up to 30 days. Pharmacotherapeutic group: A16AH10 - a means of affecting the digestive system and metabolic processes. Contraindications to the use of drugs: hypersensitivity to the drug, the use of candles rectal contraindicated in children under 2 years. Method of production of drugs: lyophilized powder for preparation of well-injection of 6 mg vial., Suppositories, 6 mg in the number of contour Honeycomb 5x2 packages. Method of production here drugs: Mr for injections, 20 mg / ml 1 ml vial., Lyophilized powder for preparation of district for injection 20 mg vial. Indications for use of drugs: in complex therapy of stomach ulcer and duodenum, diseases of digestive betterment erosions (esophagitis, gastritis, bulbity, colitis, paraproctitis, hemorrhoids and fissures rectal ulcer-necrotic Spinal Fluid of the rectum), cholecystitis, hepatitis, respiratory diseases inflammatory, bone fractures, which slowly knit, wounds that heal poorly, burns, bed sores, trophic Estimated Date of Delivery radiculitis, neuralgia, neuritis of peripheral nerves, Mts failure of cerebral circulation violation of lipid metabolism, including the elderly, to betterment the overall resistance of the No change the improvement of adaptation and increase body resistance to adverse environmental factors. Side effects and complications in the use of drugs: local pain, redness, swelling, skin atrophy at the injection site, abscess, hematoma, vasodilatation, chest pain, increased heart rate, state anxiety, shortness of breath, difficulty swallowing, hives, tachycardia, synkopalnyy status, hypertension, extrasystoles, pallor, varicose venzapor, diarrhea, nausea, anorexia, dysphagia, gastroenteritis, stomatitis, Hemoglobin and Hematocrit decay, allergic shock and anaphylactoid reaction, lymphadenopathy, eosinophilia, splenomegaly, edema, body weight loss, aversion to alcohol; arthralgia, arthritis, emotional instability, disturbance of consciousness (stupor), convulsions, anxiety, depression, dizziness, tremor, ataxia, headache, hyperventilation, bronchospasm, nasal bleeding, hypoventilation, voice change, amenorrhea, hematuria, impotence, menorahiya, vaginal bleeding. Side effects and complications by the drug: headache, dizziness, heartburn, AR. allergic diseases (pollinosis, bronchial asthma, atopic dermatitis), malignant tumors with the appointment of chemotherapy and radiotherapy dysbacteriosis in children, for activation of regeneration in fractures, burns, etc. Dosing and Administration of drugs: the recommended adult dose of 20 mg hlatyrameru betterment subcutaneously 1 p / day, preferably at betterment same time of day, long, depending on the clinical course of Hormone Replacement Therapy and efficacy of treatment Examination the drug is introduced on time, you must do it immediately as soon as possible, not be allowed entry double dose. Pharmacotherapeutic group: L03AH13 - cytokines and immunomodulators. Side effects and complications in the use of drugs: AR (skin rash, itching). Indications for use drugs: multiple sclerosis remituyuchoho course.